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Icosapent Disease Interactions

There are 3 disease interactions with icosapent.

Moderate

Icosapent (applies to icosapent) atrial fibrillation/flutter

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Arrhythmias

Icosapent is associated with an increased risk of atrial fibrillation or atrial flutter requiring hospitalization. In a cardiovascular outcomes trial, the incidence of atrial fibrillation was greater in patients with history of atrial fibrillation or atrial flutter; caution is recommended in these patients.

Moderate

Icosapent (applies to icosapent) fish allergy

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Allergies

Icosapent ethyl is obtained from the oil of fish. It is unknown if patients with allergies to fish and/or shellfish are at increased risk of an allergic reaction to this drug. Use with caution in patients with known hypersensitivity to fish and/or shellfish; advise such patients about the potential for allergic reactions to this drug.

Moderate

Icosapent (applies to icosapent) liver disease

Moderate Potential Hazard, Moderate plausibility.

In patients with liver dysfunction, ALT and AST levels should be monitored periodically during therapy with icosapent; caution is recommended in these patients.

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Icosapent drug interactions

There are 76 drug interactions with icosapent.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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