Dopamine Disease Interactions
There are 6 disease interactions with dopamine.
- Arrhythmias
- Asthmatics
- Dehydration
- Ischemic heart disease
- Peripheral vascular disease
- Pheochromocytoma
Dopamine (applies to dopamine) arrhythmias
Major Potential Hazard, High plausibility.
The use of dopamine is contraindicated in patients with uncorrected tachyarrhythmias or ventricular fibrillation. Dopamine exerts an agonistic action on the beta receptors of the heart which may lead to an increase in heart rate, atrial fibrillation, enhanced A-V conduction, ventricular ectopy, and arrhythmias.
Dopamine (applies to dopamine) asthmatics
Major Potential Hazard, Moderate plausibility.
Dopamine injection contains sodium metabisulfite, a sulfite that may cause anaphylactic symptoms and life-threatening or less severe asthmatic episodes in susceptible people, such as asthmatic patients.
Dopamine (applies to dopamine) dehydration
Major Potential Hazard, High plausibility.
The use of dopamine has been infrequently associated with significant hypotension especially in dehydrated patients secondary to beta-2 mediated vasodilation. Hypovolemia should be corrected before administering dopamine. Blood pressure and ECG should be monitored at regular intervals. Monitoring of cardiac output and pulmonary wedge pressure is recommended.
Dopamine (applies to dopamine) ischemic heart disease
Major Potential Hazard, High plausibility.
The use of dopamine may worsen ischemic heart disease. The stimulation of cardiac beta receptors may aggravate ischemic heart disease. Therapy with dopamine should be administered cautiously in patients with ischemic heart disease. Monitoring of ECG, blood pressure, urine flow, and cardiac output is recommended.
Dopamine (applies to dopamine) peripheral vascular disease
Major Potential Hazard, High plausibility. Applicable conditions: Peripheral Arterial Disease
The vasoconstrictive actions of dopamine may aggravate occlusive vascular disease (atherosclerosis, arterial embolism, Raynaud's disease, cold injury, diabetic endarteritis, or Buerger's disease). Therapy with dopamine should be administered cautiously in patients with occlusive vascular disease. Patients should be monitored for decreased circulation to the extremities (change in color or temperature of the skin).
Dopamine (applies to dopamine) pheochromocytoma
Major Potential Hazard, High plausibility.
The use of dopamine is contraindicated in patients with pheochromocytoma. The catecholamine effects of dopamine may aggravate this condition.
Dopamine drug interactions
There are 226 drug interactions with dopamine.
Dopamine alcohol/food interactions
There is 1 alcohol/food interaction with dopamine.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.