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Sevenfact Disease Interactions

There are 2 disease interactions with Sevenfact (coagulation factor viia).

Major

Coagulation factor VIIa (applies to Sevenfact) thrombosis

Major Potential Hazard, Moderate plausibility. Applicable conditions: Thrombotic/Thromboembolic Disorder, Liver Disease, Heart Disease

Serious arterial and venous thrombotic events have been reported with the use of coagulation factor VIIa. Patients at an increased risk of thromboembolic complications may include those with a history of coronary heart disease, liver disease, disseminated intravascular coagulation, post-operative immobilizations, elderly patients, and neonates. It is recommended to exercise caution when administering coagulation factor VIIa to patients at risk and the potential benefit of treatment should be weighed against the risk of these complications.

Moderate

Coagulation factor VIIa (applies to Sevenfact) allergies

Moderate Potential Hazard, Moderate plausibility.

Hypersensitivity reactions, including anaphylaxis, can occur with coagulation factor VIIa. Patients with a known hypersensitivity to mouse, hamster, or bovine proteins may be at a higher risk of hypersensitivity reactions. Discontinue infusion and administer appropriate treatment when hypersensitivity reactions occur.

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Sevenfact drug interactions

There are 8 drug interactions with Sevenfact (coagulation factor viia).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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