Skip to main content

Castor oil Disease Interactions

There are 5 disease interactions with castor oil.

Major

Castor oil (applies to castor oil) dehydration

Major Potential Hazard, High plausibility. Applicable conditions: Hyponatremia, Hypokalemia, Electrolyte Abnormalities

The use of castor oil is contraindicated in patients with dehydration or electrolyte imbalance. Castor oil is hydrolyzed to glycerol and ricinoleic acid within the small intestine. Ricinoleic acid acts on the small intestine to reduce the net absorption of fluid and electrolytes. This altered intestinal permeability caused by castor oil may produce dehydration and electrolyte imbalance.

Major

Castor oil (applies to castor oil) intestinal obstruction

Major Potential Hazard, High plausibility. Applicable conditions: Gastrointestinal Obstruction

The use of castor oil is contraindicated in patients with intestinal obstruction. Fluid and electrolyte build up in the intestinal tract due to castor oil may exacerbate intestinal obstruction.

Major

Laxatives (applies to castor oil) inflammatory bowel disease

Major Potential Hazard, Moderate plausibility.

The use of laxatives is contraindicated in patients with inflammatory bowel disease. Patients with inflammatory bowel disease may experience colonic perforation with use of stimulant laxatives.

Major

Laxatives (applies to castor oil) intestinal obstruction disorders

Major Potential Hazard, Moderate plausibility. Applicable conditions: Gastrointestinal Obstruction

The use of laxatives is contraindicated in patients with intestinal obstruction disorders. Patients with intestinal obstruction disorders may need their underlying condition treated to correct the constipation. Some laxatives require reduction in the colon to their active form to be effective which may be a problem in patients with intestinal obstruction.

Major

Stimulant laxatives (applies to castor oil) rectal bleeding

Major Potential Hazard, Moderate plausibility.

The use of stimulant laxatives is contraindicated in patients with anal or rectal fissures. These preparations may cause irritation, burning sensation, and proctitis.

Switch to professional interaction data

Castor oil drug interactions

There are 218 drug interactions with castor oil.

Report options

Loading...
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer