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Rimantadine (Oral)

Generic name: rimantadine [ ri-MAN-ta-deen ]
Brand name: Flumadine
Drug class: Adamantane antivirals

Medically reviewed by Drugs.com. Last updated on Jun 13, 2024.

Uses for rimantadine

Rimantadine is used to prevent or treat certain influenza (flu) infections (type A) in adults (17 years of age and older). It is also used to prevent flu infection (type A) in children (1 to 16 years of age). It may be given alone or along with flu shots.

Rimantadine is an antiviral. It will not work for colds, other types of flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Before using rimantadine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of rimantadine in children. However, safety and efficacy have not been established in children younger than 1 year of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of rimantadine in the elderly. However, elderly patients are more likely to have unwanted side effects (e.g., anxiety, dizziness, nausea, vomiting, stomach pain), which may require caution and an adjustment in the dose for patients receiving rimantadine.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

Proper use of rimantadine

Talk to your doctor about the possibility of getting a flu shot if you have not had one yet.

This medicine is best taken before exposure, or as soon as possible after exposure, to people who have the flu.

To help keep yourself from getting the flu, keep taking this medicine for the full time of treatment.

If you already have the flu, continue taking this medicine for the full time of treatment even if you begin to feel better after a few days. This will help to clear up your infection completely. If you stop taking this medicine too soon, your symptoms may return. This medicine should be taken for at least 5 to 7 days.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times day and night.

Shake the oral liquid well before each use. Measure the medicine with a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the oral liquid at room temperature for 14 days.

amantadine, Tamiflu, oseltamivir, Fluzone, Afluria, influenza virus vaccine, inactivated, Flucelvax, Flumadine

Precautions while using rimantadine

It is important that your doctor check the progress of you or your child at regular visits to allow changes in your dose and to check for any unwanted effects.

This medicine may cause some people to become dizzy or confused, or to have trouble concentrating. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or confused. If these reactions are especially bothersome, check with your doctor.

If your or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor.

While you are being treated with rimantadine, do not have any immunizations (vaccinations) without your doctor's approval. Live virus vaccinations should not be given for 2 days after stopping rimantadine, and this medicine should be not be given 2 weeks after receiving live vaccines.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Side Effects of rimantadine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Commonly used brand name(s)

In the U.S.

Available Dosage Forms:

Therapeutic Class: Antiviral

Chemical Class: Adamantane

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.