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Macimorelin (Oral)

Generic name: macimorelin [ ma-si-moe-REL-in ]
Brand name: Macrilen
Drug class: Growth hormones

Medically reviewed by Drugs.com. Last updated on Sep 11, 2023.

Uses for macimorelin

Macimorelin is used for the diagnosis of adult growth hormone deficiency (AGHD).

This medicine is to be given only by or under the supervision of a doctor.

Before using macimorelin

In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of macimorelin in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of macimorelin in the elderly.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this diagnostic test, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Receiving this diagnostic test with any of the following medicines is not recommended. Your doctor may decide not to use this diagnostic test or change some of the other medicines you take.

Receiving this diagnostic test with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this diagnostic test. Make sure you tell your doctor if you have any other medical problems, especially:

Proper use of macimorelin

A healthcare provider will give you this medicine in a hospital or clinic. You should drink all the medicine within 30 seconds.

Follow all instructions you are given for your scan or procedure. Your doctor may tell you not to eat or drink anything at least 8 hours before your test.

Detailed Macimorelin dosage information

Precautions while using macimorelin

It is very important that your doctor check your progress to make sure that this medicine is working properly and to check for unwanted effects.

Do not use a growth hormone medicine for at least 1 week before receiving this medicine.

Do not use armodafinil (Nuvigil®), bosentan (Tracleer®), carbamazepine (Tegretol®), efavirenz (Sustiva®), enzalutamide (Xtandi®), etravirine (Intelence®), mitotane (Lysodren®), modafinil (Provigil®), phenytoin (Dilantin®), rifampin (Rifadin®, Rimactane®), rufinamide (Banzel®), or St. John’s wort together with macimorelin. These medicines may decrease the amount of macimorelin in the blood, which may cause a false positive result to adult growth hormone deficiency test. Your doctor may tell you to stop taking these medicines for a certain period of time before using macimorelin.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Side Effects of macimorelin

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Less common

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Macimorelin side effects (more detail)

Commonly used brand name(s)

In the U.S.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer