Comparing Zoloft vs Zyprexa
| Zoloft (sertraline) | Zyprexa (olanzapine) |
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| Zoloft (sertraline) | Zyprexa (olanzapine) |
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Prescription only
Zoloft is a brand name for sertraline which is an effective antidepressant with less potential for drowsiness than many other antidepressants. It belongs to the group of medicines called selective... View more |
Prescription only
Zyprexa is a brand (trade) name for olanzapine which is an antipsychotic that may be used to treat schizophrenia or bipolar disorder. Weight gain is common in people who take Zyprexa. Prescribed for... View more |
Related suggestions Depression
Major Depressive Disorder
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| More about Zoloft (sertraline) | More about Zyprexa (olanzapine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Zoloft has an average rating of 7.3 out of 10 from a total of 1958 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
Zyprexa has an average rating of 5.9 out of 10 from a total of 416 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Side Effects | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Zoloft prices |
View all Zyprexa prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other olanzapine brands include: Zyprexa Intramuscular, Zyprexa Relprevv, Zyprexa Zydis | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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66 hours |
54 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 670 drugs are known to interact with Zoloft:
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A total of 661 drugs are known to interact with Zyprexa:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 30, 1991 |
September 30, 1996 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.