Comparing Wellbutrin vs Zyban
| Wellbutrin (bupropion) | Zyban (bupropion) |
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| Wellbutrin (bupropion) | Zyban (bupropion) |
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Prescription only
Wellbutrin may be used in the treatment of depression; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black box warning because it may cause... View more |
Prescription only
Prescribed for Smoking Cessation. Zyban may also be used for purposes not listed in this medication guide. |
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| More about Wellbutrin (bupropion) | More about Zyban (bupropion) | |
| Ratings & Reviews | ||
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Wellbutrin has an average rating of 6.8 out of 10 from a total of 756 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 23% reported a negative effect. |
Zyban has an average rating of 8.0 out of 10 from a total of 129 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||
View all Wellbutrin side effects |
View all Zyban side effects |
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| Drug Class | ||
| Generic Availability | ||
| Lower cost generic approved | ||
| Pricing and Coupons * Prices are without insurance | ||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||
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| Brand Names | ||
| Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | |
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||
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30 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||
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A total of 527 drugs are known to interact with Wellbutrin:
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A total of 527 drugs are known to interact with Zyban:
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| Alcohol/Food/Lifestyle Interactions | ||
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| Disease Interactions | ||
| First Approval Date | ||
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December 30, 1985 |
May 14, 1997 |
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| WADA Class View classifications | ||
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N/A |
N/A |
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| More Information | ||
| Patient Resources | ||
| Professional Resources | ||
| Related Treatment Guide | ||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.