Sorafenib Alternatives Compared
| Sorafenib | Nexavar (sorafenib) | Opdivo (nivolumab) |
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| Sorafenib | Nexavar (sorafenib) | Opdivo (nivolumab) |
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Prescription only
Prescribed for Hepatic Tumor, Thyroid Cancer, Hepatocellular Carcinoma, Renal Cell Carcinoma. Sorafenib may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Hepatic Tumor, Thyroid Cancer, Hepatocellular Carcinoma, Renal Cell Carcinoma. Nexavar may also be used for purposes not listed in this medication guide. |
Prescription only
Opdivo is an immune checkpoint inhibitor that may be used to treat many different cancers including melanoma, bladder cancer, liver cancer, and lung cancer. Fatigue, skin conditions, a cough, upper... View more |
Related suggestions Hepatocellular Carcinoma
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| More about Sorafenib | More about Nexavar (sorafenib) | More about Opdivo (nivolumab) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Sorafenib has an average rating of 5.5 out of 10 from a total of 15 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 40% reported a negative effect. |
Nexavar has an average rating of 5.4 out of 10 from a total of 14 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 43% reported a negative effect. |
Opdivo has an average rating of 5.8 out of 10 from a total of 94 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 40% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Sorafenib side effects |
View all Nexavar side effects |
View all Opdivo side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Sorafenib prices |
View all Nexavar prices |
View all Opdivo prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Nexavar |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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48 hours |
48 hours |
640.8 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 426 drugs are known to interact with Sorafenib:
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A total of 426 drugs are known to interact with Nexavar:
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A total of 588 drugs are known to interact with Opdivo:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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December 01, 2005 |
December 01, 2005 |
December 22, 2014 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.