Comparing Skelaxin vs Zanaflex
Skelaxin | Zanaflex |
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Skelaxin (metaxalone) | Zanaflex (tizanidine) |
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Prescription only
Prescribed for Muscle Spasm. Skelaxin may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Cluster Headaches, Muscle Spasm. Zanaflex may also be used for purposes not listed in this medication guide. |
Related suggestions Muscle Spasm (Involuntary Hypertonicity)
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More about Skelaxin (metaxalone) | More about Zanaflex (tizanidine) | |
Ratings & Reviews | ||
Skelaxin has an average rating of 7.8 out of 10 from a total of 85 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 11% reported a negative effect. |
Zanaflex has an average rating of 7.6 out of 10 from a total of 115 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 12% reported a negative effect. |
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Drug Class | ||
Side Effects | ||
See also: Skelaxin side effects in more detail. |
See also: Zanaflex side effects in more detail. |
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Generic Availability | ||
Lower cost generic approved | ||
Pricing and Coupons * Prices are without insurance | ||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Forms Available | ||
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Brand Names | ||
Other metaxalone brands include: Metaxall |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||
3 hours |
2.5 hours |
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CSA Schedule ** View glossary of terms | ||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||
Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||
A total of 315 drugs are known to interact with Skelaxin:
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A total of 615 drugs are known to interact with Zanaflex:
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Alcohol/Food/Lifestyle Interactions | ||
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Disease Interactions | ||
First Approval Date | ||
August 13, 1962 |
November 27, 1996 |
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WADA Class View World Anti-Doping Agency classifications. | ||
N/A |
N/A |
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More Information | ||
Patient resources | ||
Professional Resources | ||
Related Treatment Guide | ||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.