Comparing Quartette vs Seasonale

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Quartette (ethinyl estradiol / levonorgestrel)	Seasonale (ethinyl estradiol / levonorgestrel)	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Quartette (ethinyl estradiol / levonorgestrel)	Seasonale (ethinyl estradiol / levonorgestrel)	Enter another drug to compare
Prescription only Prescribed for Birth Control. Quartette may also be used for purposes not listed in this medication guide.	Prescription only Prescribed for Endometriosis, Polycystic Ovary Syndrome, Abnormal Uterine Bleeding, Birth Control, Ovarian Cysts, Gonadotropin Inhibition. Seasonale may also be used for purposes not listed in this... View more	Related suggestions Birth Control Mirena Nexplanon Lo Loestrin Fe NuvaRing Sprintec Depo Provera
More about Quartette (ethinyl estradiol / levonorgestrel)	More about Seasonale (ethinyl estradiol / levonorgestrel)
Ratings & Reviews
Be the first to share your experience with this drug.	Seasonale has an average rating of 5.8 out of 10 from a total of 55 ratings on Drugs.com. 42% of reviewers reported a positive effect, while 33% reported a negative effect.
Review this drug	View all 55 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
View all Quartette side effects	Bleeding (41.8%) Cramps (30.9%) Spotting (29.1%) Weight gain (16.4%) Sexual dysfunction (12.7%) Acne (10.9%) Headaches (10.9%) View all Seasonale side effects
Drug Class
Contraceptives	Contraceptives
Generic Availability
Lower cost generic approved	Lower cost generic approved
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
Oral tablet	Oral tablet
Brand Names
Other ethinyl estradiol / levonorgestrel brands include: Afirmelle, Altavera, Amethia, Amethia Lo, Amethyst, Ashlyna, Aubra, Aubra EQ, Aviane, Ayuna, Balcoltra, Camrese, CamreseLo, Cerinta, Chateal, Chateal EQ, Daysee, Delyla, Dolishale, Elifemme, Enpresse, Falmina, Fayosim, Iclevia, Introvale, Jaimiess, Jolessa, Joyeaux, Kurvelo, Larissia, Lessina, Levlen, Levonest, Levora, Lillow, Lo Simpesse, LoJaimiess, LoSeasonique, Lutera, Marlissa, Minzoya, Myzilra, Orsythia, Portia, Rivelsa, Rosyrah, Seasonale, Seasonique, Setlakin, Simpesse, Sronyx, Trivora, Twirla, Tyblume, Vienva View more	Other ethinyl estradiol / levonorgestrel brands include: Afirmelle, Altavera, Amethia, Amethia Lo, Amethyst, Ashlyna, Aubra, Aubra EQ, Aviane, Ayuna, Balcoltra, Camrese, CamreseLo, Cerinta, Chateal, Chateal EQ, Daysee, Delyla, Dolishale, Elifemme, Enpresse, Falmina, Fayosim, Iclevia, Introvale, Jaimiess, Jolessa, Joyeaux, Kurvelo, Larissia, Lessina, Levlen, Levonest, Levora, Lillow, Lo Simpesse, LoJaimiess, LoSeasonique, Lutera, Marlissa, Minzoya, Myzilra, Orsythia, Portia, Quartette, Rivelsa, Rosyrah, Seasonique, Setlakin, Simpesse, Sronyx, Trivora, Twirla, Tyblume, Vienva View more
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
45 hours	45 hours
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
X Category X Not for use in pregnancy See the full pregnancy warnings document.	X Category X Not for use in pregnancy See the full pregnancy warnings document.
Drug Interactions
A total of 492 drugs are known to interact with Quartette: 76 major drug interactions (197 brand and generic names) 367 moderate drug interactions (1379 brand and generic names) 49 minor drug interactions (527 brand and generic names)	A total of 492 drugs are known to interact with Seasonale: 76 major drug interactions (197 brand and generic names) 367 moderate drug interactions (1379 brand and generic names) 49 minor drug interactions (527 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Grapefruit juice may increase the blood levels of certain medications such as levonorgestrel. You... View more	Grapefruit juice may increase the blood levels of certain medications such as levonorgestrel. You... View more
Disease Interactions
Smoking Abnormal genital bleeding Abnormal vaginal bleeding Carcinomas (estrogenic) Hypercalcemia in breast cancer Hypertension Thromboembolism/cardiovascular Hepatic neoplasms Breast malignancy Liver disease Angioedema Gallbladder disease Hypercalcemia Hyperlipidemia Liver disease Melasma Depression Fluid retention Glucose intolerance Retinal thrombosis Thyroid function tests Cardiovascular disease Hyperlipidemia Weight gain	Smoking Abnormal genital bleeding Abnormal vaginal bleeding Carcinomas (estrogenic) Hypercalcemia in breast cancer Hypertension Thromboembolism/cardiovascular Hepatic neoplasms Breast malignancy Liver disease Angioedema Gallbladder disease Hypercalcemia Hyperlipidemia Liver disease Melasma Depression Fluid retention Glucose intolerance Retinal thrombosis Thyroid function tests Cardiovascular disease Hyperlipidemia Weight gain
First Approval Date
March 28, 2013	September 05, 2003
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pregnancy warnings Drug images En español	Side effects Drug interactions Dosage Pregnancy warnings Drug images Support group
Patient Resources
Quartette uses	Seasonale uses
Professional Resources
Prescribing information	Prescribing information
Related Treatment Guide
Birth Control	Endometriosis Polycystic Ovary Syndrome Abnormal Uterine Bleeding Birth Control Ovarian Cysts Gonadotropin Inhibition

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

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Comparing Quartette vs Seasonale

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