Comparing Prozac vs Wellbutrin
| Prozac (fluoxetine) | Wellbutrin (bupropion) |
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| Prozac (fluoxetine) | Wellbutrin (bupropion) |
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Prescription only
Prozac may be used for the treatment of depression and other mood disorders. It is more likely to cause insomnia than drowsiness. Prescribed for Anxiety and Stress, Major Depressive Disorder... View more |
Prescription only
Wellbutrin may be used in the treatment of depression; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black box warning because it may cause... View more |
Related suggestions Depression
Major Depressive Disorder
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| More about Prozac (fluoxetine) | More about Wellbutrin (bupropion) | ||||||||
| Ratings & Reviews | |||||||||
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Prozac has an average rating of 7.2 out of 10 from a total of 1239 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 20% reported a negative effect. |
Wellbutrin has an average rating of 6.8 out of 10 from a total of 756 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Prozac side effects |
View all Wellbutrin side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Prozac prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
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N/A |
Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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210 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 681 drugs are known to interact with Prozac:
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A total of 527 drugs are known to interact with Wellbutrin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 29, 1987 |
December 30, 1985 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.