Comparing Pristiq vs Prozac
| Pristiq (desvenlafaxine) | Prozac (fluoxetine) |
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| Pristiq (desvenlafaxine) | Prozac (fluoxetine) |
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Prescription only
Prescribed for Major Depressive Disorder, Depression. Pristiq may also be used for purposes not listed in this medication guide. |
Prescription only
Prozac may be used for the treatment of depression and other mood disorders. It is more likely to cause insomnia than drowsiness. Prescribed for Anxiety and Stress, Major Depressive Disorder... View more |
Related suggestions Depression
Major Depressive Disorder
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| More about Pristiq (desvenlafaxine) | More about Prozac (fluoxetine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Pristiq has an average rating of 6.9 out of 10 from a total of 1127 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 22% reported a negative effect. |
Prozac has an average rating of 7.2 out of 10 from a total of 1239 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Pristiq side effects |
View all Prozac side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Pristiq prices |
View all Prozac prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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11 hours |
210 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 481 drugs are known to interact with Pristiq:
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A total of 681 drugs are known to interact with Prozac:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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February 29, 2008 |
December 29, 1987 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.