Comparing Plegridy vs Rebif
| Plegridy (peginterferon beta-1a) | Rebif (interferon beta-1a) |
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| Plegridy (peginterferon beta-1a) | Rebif (interferon beta-1a) |
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Prescription only
Plegridy (peginterferon beta-1a) may be used to treat multiple sclerosis (MS) in adults and can be self-administered either subcutaneously or intramuscularly. Injection-site reactions with SC... View more |
Prescription only
Rebif may be used to reduce the frequency of exacerbations of MS and delay the progression of the disease in adults. It is usually self-administered by SC injection three times per week and the most... View more |
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| More about Plegridy (peginterferon beta-1a) | More about Rebif (interferon beta-1a) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Plegridy has an average rating of 4.8 out of 10 from a total of 14 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 43% reported a negative effect. |
Rebif has an average rating of 6.8 out of 10 from a total of 29 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 24% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Plegridy side effects |
View all Rebif side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Plegridy prices |
View all Rebif prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other interferon beta-1a brands include: Avonex, Avonex Pen, Avonex Prefilled Syringe, Rebif Rebidose | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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78 hours |
3 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 335 drugs are known to interact with Plegridy:
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A total of 339 drugs are known to interact with Rebif:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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August 15, 2014 |
March 07, 2002 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.