Comparing Phenobarbital vs Zonisamide
| Phenobarbital | Zonisamide |
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| Phenobarbital | Zonisamide |
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Prescription only
Prescribed for Epilepsy, Hyperbilirubinemia, Sedation, Seizures, Insomnia. Phenobarbital may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Migraine Prevention, Epilepsy, Benign Essential Tremor, Parkinsonian Tremor, Seizures. Zonisamide may also be used for purposes not listed in this medication guide. |
Related suggestions Seizures
Popular comparisons
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| More about Phenobarbital | More about Zonisamide | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Phenobarbital has an average rating of 9.1 out of 10 from a total of 35 ratings on Drugs.com. 91% of reviewers reported a positive effect, while 6% reported a negative effect. |
Zonisamide has an average rating of 5.6 out of 10 from a total of 146 ratings on Drugs.com. 39% of reviewers reported a positive effect, while 37% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Phenobarbital side effects |
View all Zonisamide side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Phenobarbital prices |
View all Zonisamide prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Sezaby | Zonegran, Zonisade | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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118 hours |
63 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 796 drugs are known to interact with Phenobarbital:
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A total of 411 drugs are known to interact with Zonisamide:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
March 27, 2000 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.