Comparing Phenobarbital vs Phenytoin
| Phenobarbital | Phenytoin |
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| Phenobarbital | Phenytoin |
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Prescription only
Prescribed for Epilepsy, Hyperbilirubinemia, Sedation, Seizures, Insomnia. Phenobarbital may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Epilepsy, Seizures, Status Epilepticus, Cluster-Tic Syndrome, Anxiety, Seizure Prophylaxis During or Following Neurosurgery, Arrhythmia, Neurosurgery, Myotonia Congenita, Peripheral... View more |
Related suggestions Seizures
Popular comparisons
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| More about Phenobarbital | More about Phenytoin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Phenobarbital has an average rating of 9.1 out of 10 from a total of 35 ratings on Drugs.com. 91% of reviewers reported a positive effect, while 6% reported a negative effect. |
Phenytoin has an average rating of 7.5 out of 10 from a total of 115 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Phenobarbital side effects |
View all Phenytoin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Phenobarbital prices |
View all Phenytoin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Sezaby | Di-Phen, Dilantin, Phenytek, Phenytoin Sodium, Phenytoin Sodium, Extended Release | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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118 hours |
15 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 796 drugs are known to interact with Phenobarbital:
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A total of 850 drugs are known to interact with Phenytoin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
January 06, 1953 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.