Comparing Pepcid vs Zyrtec
| Pepcid (famotidine) | Zyrtec (cetirizine) |
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| Pepcid (famotidine) | Zyrtec (cetirizine) |
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Prescription only
Prescribed for Erosive Esophagitis, Duodenal Ulcer, GERD, Duodenal Ulcer Prophylaxis, Indigestion, Pathological Hypersecretory Conditions, Peptic Ulcer, Stomach Ulcer, Upper GI Hemorrhage... View more |
Prescription and OTC
Zyrtec is an antihistamine that effectively treats allergic reactions such as hay fever or skin reactions caused by insect bites. Although drowsiness with Zyrtec is uncommon, Zyrtec is more likely... View more |
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| More about Pepcid (famotidine) | More about Zyrtec (cetirizine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Pepcid has an average rating of 6.0 out of 10 from a total of 10 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 30% reported a negative effect. |
Zyrtec has an average rating of 5.8 out of 10 from a total of 197 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 36% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Pepcid side effects |
View all Zyrtec side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Lower cost generic approved | Lower cost generic approved | ||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Pepcid prices |
View all Zyrtec prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other famotidine brands include: Acid Control, Acid Controller Maximum Strength, Acid Controller Original Strength, Acid Reducer Maximum Strength, Acid Reducer Original Strength, Acid Reducer-Famotidine, Heartburn Relief, Heartburn Relief Maximum Strength, Pepcid AC, Pepcid AC Chewable Tablets, Pepcid AC Maximum Strength, Pepcid AC Maximum Strength Tablets, Pepcid Oral Suspension, Zantac 360 View more | Other cetirizine brands include: All Day Allergy, All Day Allergy Children's, Aller-Tec, Aller-Tec Children's, Alleroff, Children's Allergy Relief, Equate Allergy Relief, PediaCare Children's 24-Hour Allergy, Quzyttir, Zyrtec Hives View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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4 hours |
10.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 312 drugs are known to interact with Pepcid:
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A total of 254 drugs are known to interact with Zyrtec:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 15, 1986 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.