Comparing Paroxetine vs Zoloft
Paroxetine | Zoloft |
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Paroxetine | Zoloft (sertraline) |
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Prescription only
Paroxetine may be used in the treatment of depression or anxiety disorders. Common side effects include headaches and nausea. Taking paroxetine with other medications such as tramadol that also... View more |
Prescription only
Zoloft is a brand name for sertraline which is an effective antidepressant with less potential for drowsiness than many other antidepressants. It belongs to the group of medicines called selective... View more |
Related suggestions Depression
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Obsessive Compulsive Disorder
Popular comparisons
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More about Paroxetine | More about Zoloft (sertraline) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Paroxetine has an average rating of 7.1 out of 10 from a total of 1525 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 20% reported a negative effect. |
Zoloft has an average rating of 7.3 out of 10 from a total of 1950 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 19% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: paroxetine side effects in more detail. |
See also: Zoloft side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all paroxetine prices |
View all Zoloft prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Brisdelle, Paxil, Paxil CR |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
21 hours |
66 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
Excluding Brisdelle
Category X
Not for use in pregnancy
Brisdelle See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 505 drugs are known to interact with paroxetine:
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A total of 670 drugs are known to interact with Zoloft:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
December 29, 1992 |
December 30, 1991 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.