Opdivo Alternatives Compared
| Opdivo (nivolumab) | Pembrolizumab | Imfinzi (durvalumab) |
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| Opdivo (nivolumab) | Pembrolizumab | Imfinzi (durvalumab) |
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Prescription only
Opdivo is an immune checkpoint inhibitor that may be used to treat many different cancers including melanoma, bladder cancer, liver cancer, and lung cancer. Fatigue, skin conditions, a cough, upper... View more |
Prescription only
Prescribed for Bladder Cancer, Cervical Cancer, Breast Cancer, Biliary Tract Tumor, Colorectal Cancer, Endometrial Cancer, Esophageal Carcinoma, Gastric Cancer, Head and Neck Cancer, Hepatocellular... View more |
Prescription only
Prescribed for Non Small Cell Lung Cancer, Hepatocellular Carcinoma, Small Cell Lung Cancer, Biliary Tract Tumor, Endometrial Cancer. Imfinzi may also be used for purposes not listed in this medication guide. View more |
Related suggestions Popular comparisons
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| More about Opdivo (nivolumab) | More about Pembrolizumab | More about Imfinzi (durvalumab) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Opdivo has an average rating of 5.4 out of 10 from a total of 90 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 45% reported a negative effect. |
Pembrolizumab has an average rating of 5.1 out of 10 from a total of 267 ratings on Drugs.com. 42% of reviewers reported a positive effect, while 47% reported a negative effect. |
Imfinzi has an average rating of 8.7 out of 10 from a total of 6 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all Opdivo prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Imfinzi prices |
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| Dosage Forms Available | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
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N/A |
Keytruda |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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640.8 hours |
624 hours |
408 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 403 drugs are known to interact with Opdivo:
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A total of 403 drugs are known to interact with Pembrolizumab:
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A total of 439 drugs are known to interact with Imfinzi:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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December 22, 2014 |
N/A |
May 01, 2017 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.