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Nuzyra Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Nuzyra (omadacycline) Levofloxacin Clarithromycin
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Nuzyra (omadacycline) Levofloxacin Clarithromycin
Prescription only

Prescribed for Skin and Structure Infection, Pneumonia. Nuzyra may also be used for purposes not listed in this medication guide.

Prescription only

Levofloxacin treats a wide range of bacterial infections; however, it can cause some very severe and potentially irreversible side effects such as tendonitis or tendon rupture, and should only be... View more

Prescription only

Prescribed for Bronchitis, Bacterial Endocarditis Prevention, Dental Abscess, Follicular Lymphoma, Helicobacter Pylori Infection, Legionella Pneumonia, Middle Ear Infections, Mycobacterium... View more

More about Nuzyra (omadacycline) More about Levofloxacin More about Clarithromycin
Ratings & Reviews

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Levofloxacin has an average rating of 5.1 out of 10 from a total of 742 ratings on Drugs.com. 38% of reviewers reported a positive effect, while 45% reported a negative effect.

Clarithromycin has an average rating of 5.4 out of 10 from a total of 851 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 35% reported a negative effect.

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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Nuzyra side effects

View all Levofloxacin side effects

View all Clarithromycin side effects
Drug Class
Generic Availability

No lower cost generic approved

Lower cost generic

Lower cost generic
Pricing and Coupons * Prices are without insurance
Quantity 6 tablet
Strength 150 mg
Per unit* $282.59
Cost* $1,695.54

View all Nuzyra prices

Quantity 3 tablet
Strength 500 mg
Per unit* $6.00
Cost* $18.01

View all Levofloxacin prices

Quantity 30 each
Strength 500 mg
Per unit* $2.26
Cost* $67.75

View all Clarithromycin prices

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Dosage Forms
  • Intravenous powder for injection
  • Oral tablet
  • Intravenous solution
  • Oral solution
  • Oral tablet
  • Oral powder for reconstitution
  • Oral tablet
  • Oral tablet, extended release
Brand Names

N/A

N/A

 Biaxin XL
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

21.7 hours

6 hours

7 hours
CSA Schedule 1 View glossary of CSA terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category

Summary unavailable.

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
Drug Interactions

A total of 130 drugs are known to interact with Nuzyra:

  • 15 major drug interactions (45 brand and generic names)
  • 115 moderate drug interactions (1900 brand and generic names)

A total of 524 drugs are known to interact with Levofloxacin:

  • 117 major drug interactions (504 brand and generic names)
  • 340 moderate drug interactions (2820 brand and generic names)
  • 67 minor drug interactions (166 brand and generic names)

A total of 712 drugs are known to interact with Clarithromycin:

  • 277 major drug interactions (985 brand and generic names)
  • 385 moderate drug interactions (1495 brand and generic names)
  • 50 minor drug interactions (167 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Do not take iron supplements, multivitamins, calcium supplements, or antacids within 4 hours before... View more
  • When levoFLOXacin as the oral solution is given with enteral (tube) feedings, levoFLOXacin may not... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease Interactions
First Approval Date

October 02, 2018

N/A

October 31, 1991
WADA Class View classifications

N/A

N/A

N/A
More Information
Patient Resources
Professional Resources
Related Treatment Guide

1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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