Comparing Norethindrone vs Prometrium
| Norethindrone | Prometrium (progesterone) |
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| Norethindrone | Prometrium (progesterone) |
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Prescription only
Prescribed for Abnormal Uterine Bleeding, Endometriosis, Amenorrhea, Gender Affirming Hormone Therapy, Birth Control. Norethindrone may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Prescribed for Progesterone Insufficiency, Perimenopausal Symptoms, Amenorrhea, Endometrial Hyperplasia - Prophylaxis, Uterine Bleeding, Premature Labor. Prometrium may also be used for purposes not... View more |
Related suggestions |
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| More about Norethindrone | More about Prometrium (progesterone) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Norethindrone has an average rating of 4.9 out of 10 from a total of 1571 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 45% reported a negative effect. |
Prometrium has an average rating of 7.0 out of 10 from a total of 37 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Norethindrone side effects |
View all Prometrium side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Norethindrone prices |
View all Prometrium prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Affodel, Camila, Deblitane, Emzahh, Errin, Gallifrey, Heather, Incassia, Jencycla, Lyleq, Lyza, Meleya, Nor-QD, Norlyda, Norlyroc, Orquidea, Sharobel, Tulana View more | Other progesterone brands include: Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Milprosa | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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10 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 263 drugs are known to interact with Norethindrone:
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A total of 211 drugs are known to interact with Prometrium:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 21, 1982 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.