Comparing Mirena vs Skyla
| Mirena (levonorgestrel) | Skyla (levonorgestrel) |
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| Mirena (levonorgestrel) | Skyla (levonorgestrel) |
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Prescription only
Prescribed for Heavy Menstrual Bleeding, Birth Control. Mirena may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Birth Control. Skyla may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Mirena (levonorgestrel) | More about Skyla (levonorgestrel) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Mirena has an average rating of 6.1 out of 10 from a total of 2624 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 32% reported a negative effect. |
Skyla has an average rating of 6.9 out of 10 from a total of 1537 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 19% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Mirena side effects |
View all Skyla side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Mirena prices |
View all Skyla prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, Curae, EContra One-Step, Fallback Solo, Her Style, Julie, Kyleena, Liletta, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Optionelle, Plan B One-Step, PostDay One-Step, SheWise, Skyla, Take Action View more | Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, Curae, EContra One-Step, Fallback Solo, Her Style, Julie, Kyleena, Liletta, Mirena, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Optionelle, Plan B One-Step, PostDay One-Step, SheWise, Take Action View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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45 hours |
45 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 258 drugs are known to interact with Mirena:
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A total of 258 drugs are known to interact with Skyla:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.