Milk thistle Alternatives Compared
| Milk thistle | Ursodiol | Actigall (ursodiol) |
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| Milk thistle | Ursodiol | Actigall (ursodiol) |
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Over-the-counter
Used for Gallbladder Disease, Herbal Supplementation, Infectious Gastroenteritis. Milk thistle may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Primary Biliary Cholangitis, Gallbladder Disease, Nonalcoholic Steatohepatitis. Ursodiol may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Primary Biliary Cholangitis, Gallbladder Disease. Actigall may also be used for purposes not listed in this medication guide. |
Related suggestions Gallbladder Disease
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| More about Milk thistle | More about Ursodiol | More about Actigall (ursodiol) | ||||||||
| Ratings & Reviews | ||||||||||
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Milk thistle has an average rating of 7.0 out of 10 from a total of 7 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 14% reported a negative effect. |
Ursodiol has an average rating of 8.0 out of 10 from a total of 32 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 13% reported a negative effect. |
Actigall has an average rating of 9.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||
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View all Milk thistle side effects |
View all Ursodiol side effects |
View all Actigall side effects |
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| Drug Class | ||||||||||
| Generic Availability | ||||||||||
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N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Ursodiol prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||||||||||
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N/A |
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| Brand Names | ||||||||||
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N/A |
Actigall, Reltone, Urso, Urso Forte | Other ursodiol brands include: Reltone, Urso, Urso Forte | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||
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N/A |
139.2 hours |
139.2 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||
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Category N
Not classified
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||
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A total of 5 drugs are known to interact with Milk thistle:
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A total of 7 drugs are known to interact with Ursodiol:
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A total of 7 drugs are known to interact with Actigall:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||
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N/A |
December 31, 1987 |
December 31, 1987 |
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| WADA Class View classifications | ||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||
| Patient Resources | ||||||||||
| Professional Resources | ||||||||||
| Related Treatment Guide | ||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.