Comparing Metoprolol vs Nifedipine

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Metoprolol	Nifedipine	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Metoprolol	Nifedipine	Enter another drug to compare
Prescription only Metoprolol is available as two different salts: metoprolol tartrate and metoprolol succinate. These two salts are not interchangeable because they have different dosages, durations of action, and... View more	Prescription only Nifedipine is used in the treatment of vasospastic angina and occasionally for chronic unstable angina as an add-on to other treatments. It should not be used to rapidly drop blood pressure as this... View more	Related suggestions High Blood Pressure (Hypertension) Lisinopril Amlodipine Losartan Hydrochlorothiazide Atenolol Norvasc Migraine Prevention (Migraine Prophylaxis) Topiramate Topamax Propranolol Aimovig Amitriptyline Botox Angina Pectoris Prophylaxis Isosorbide mononitrate Aspirin Nitroglycerin Bisoprolol Diltiazem Isosorbide dinitrate Popular comparisons Metoprolol vs amlodipine Metoprolol vs diltiazem Metoprolol vs atenolol Metoprolol vs digoxin Metoprolol vs bisoprolol Metoprolol vs Bystolic
More about Metoprolol	More about Nifedipine
Ratings & Reviews
Metoprolol has an average rating of 5.8 out of 10 from a total of 653 ratings on Drugs.com. 41% of reviewers reported a positive effect, while 33% reported a negative effect.	Nifedipine has an average rating of 4.9 out of 10 from a total of 161 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 44% reported a negative effect.
View all 653 reviews	View all 161 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Tiredness (15.9%) Dizziness (11.8%) Fatigue (9.3%) Shortness of breath (8.9%) Anxiety (8.7%) Heart palpitations (7.5%) Insomnia (7.4%) View all Metoprolol side effects	Headaches (24.8%) Swelling (15.5%) Dizziness (13.7%) Increased heart rate (10.6%) Insomnia (9.3%) Heart palpitations (8.7%) Shortness of breath (8.7%) View all Nifedipine side effects
Drug Class
Cardioselective beta blockers	Calcium channel blockers
Generic Availability
N/A	Lower cost generic
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
N/A	Oral capsule Oral tablet, extended release
Brand Names
Kapspargo Sprinkle, Lopressor, Metoprolol Succinate ER, Metoprolol Tartrate, Toprol-XL	Afeditab CR, Procardia, Procardia XL
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
4 hours	5 hours
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
C Category C Risk cannot be ruled out See the full pregnancy warnings document.	C Category C Risk cannot be ruled out See the full pregnancy warnings document.
Drug Interactions
A total of 544 drugs are known to interact with Metoprolol: 28 major drug interactions (134 brand and generic names) 477 moderate drug interactions (3272 brand and generic names) 39 minor drug interactions (255 brand and generic names)	A total of 623 drugs are known to interact with Nifedipine: 27 major drug interactions (107 brand and generic names) 547 moderate drug interactions (3221 brand and generic names) 49 minor drug interactions (157 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Food can enhance the levels of metoprolol in your body. You should take metoprolol at the same... View more	You should avoid or limit the consumption of grapefruit and grapefruit juice if you are receiving... View more NIFEdipine and alcohol may have additive effects in lowering your blood pressure. You may... View more
Disease Interactions
Bradyarrhythmia/AV block Cardiogenic shock/hypotension CHF Diabetes Hemodialysis Hypersensitivity Ischemic heart disease PVD Liver disease Cerebrovascular insufficiency Glaucoma Hyperlipidemia Hyperthyroidism Hyperthyroidism PKs Myasthenia gravis Pheochromocytoma Psoriasis Tachycardia Asthma/COPD	Aortic stenosis Cardiogenic shock/hypotension Coronary artery disease Liver disease Hypertension Myocardial infarction CHF/AMI Renal dysfunction GI narrowing
First Approval Date
August 07, 1978	December 31, 1981
WADA Class View classifications
P1 - Beta-Blockers	N/A
More Information
Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings Drug images Support group En español	Side effects Drug interactions Dosage Pricing and coupons Pregnancy warnings Breastfeeding warnings Drug images Support group
Patient Resources
Metoprolol uses Advanced reading	Nifedipine uses
Professional Resources
Monograph (AHFS) Prescribing information	Monograph (AHFS) Prescribing information
Related Treatment Guide
Atrial Fibrillation Heart Failure Angina Aortic Aneurysm High Blood Pressure Angina Pectoris Prophylaxis Heart Attack Benign Essential Tremor Left Ventricular Dysfunction Migraine Prevention Mitral Valve Prolapse Premature Ventricular Depolarizations Supraventricular Tachycardia Tapering Regimen show all	High Blood Pressure Hypertensive Emergency Hypertrophic Cardiomyopathy Angina Pectoris Prophylaxis Migraine Prevention Premature Labor Raynaud's Syndrome

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

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Comparing Metoprolol vs Nifedipine

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