Comparing Losartan vs Metformin

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Losartan	Metformin	Enter another drug to compare

Losartan

Metformin

Prescription only

Losartan works on a hormone called angiotensin II to lower blood pressure and may also improve kidney function in some people. People being initiated on losartan should be adequately rehydrated and... View more

Prescription only

Metformin improves how the body responds to insulin and it is used to treat type 2 diabetes. Taste disturbances, diarrhea, and other stomach-related side effects are common side effects. Metformin is... View more

More about Losartan

More about Metformin

Ratings & Reviews

Losartan has an average rating of 4.5 out of 10 from a total of 578 ratings on Drugs.com. 26% of reviewers reported a positive effect, while 48% reported a negative effect.

Metformin has an average rating of 6.8 out of 10 from a total of 655 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 19% reported a negative effect.

View all 578 reviews

View all 655 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Dizziness (14.9%)
Anxiety (14.7%)
Tiredness (12.6%)
Headaches (12.1%)
Cough (11.9%)
Pain (10.9%)
Insomnia (8.3%)

View all Losartan side effects

Diarrhea (25.6%)
Nausea (15.3%)
Upset stomach (9.8%)
Stomach pain (4.7%)
Gas (4.6%)
Headaches (4.4%)
Cramps (3.7%)

View all Metformin side effects

Drug Class

Angiotensin receptor blockers

Non-sulfonylureas

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	50 each
Strength	50 mg
Per unit^*	$0.64
Cost^*	$32.05

View all Losartan prices

Quantity	100 each
Strength	500 mg
Per unit^*	$0.15 - $0.24
Cost^*	$15.37 - $24.08

View all Metformin prices

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Dosage Forms

Oral tablet

Oral solution
Oral tablet
Oral tablet, extended release

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

4.4 hours

4.5 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Drug Interactions

A total of 324 drugs are known to interact with Losartan:

32 major drug interactions (165 brand and generic names)
276 moderate drug interactions (1331 brand and generic names)
16 minor drug interactions (39 brand and generic names)

A total of 377 drugs are known to interact with Metformin:

24 major drug interactions (129 brand and generic names)
344 moderate drug interactions (1793 brand and generic names)
9 minor drug interactions (35 brand and generic names)

Alcohol/Food/Lifestyle Interactions

If you are taking losartan you should avoid potassium-containing salt substitutes or... View more
Losartan and alcohol may have additive effects in lowering your blood pressure. You may experience... View more

MetFORMIN should be taken with meals, and excessive alcohol intake (either short-term binge... View more

Disease Interactions

First Approval Date

April 14, 1995

March 03, 1995

WADA Class View classifications

N/A

More Information

Patient Resources

Losartan uses

Metformin uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Losartan vs Metformin

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