Comparing Lisdexamfetamine vs Methylphenidate
Lisdexamfetamine | Methylphenidate |
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Lisdexamfetamine | Methylphenidate |
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Prescription only
Lisdexamfetamine is a stimulant that may be used for the treatment of ADHD and BED; however, its use is limited by its risk of dependence, withdrawal syndrome, and potential for serious cardiac... View more |
Prescription only
Methylphenidate can help improve symptoms of ADHD but may cause dependence and side effects include a headache, loss of appetite, and sleeplessness. It is recommended that methylphenidate should not... View more |
Related suggestions Depression
ADHD (Attention Deficit Hyperactivity Disorder)
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More about Lisdexamfetamine | More about Methylphenidate | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Lisdexamfetamine has an average rating of 7.5 out of 10 from a total of 1072 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 16% reported a negative effect. |
Methylphenidate has an average rating of 7.2 out of 10 from a total of 1070 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 17% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: lisdexamfetamine side effects in more detail. |
See also: methylphenidate side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all lisdexamfetamine prices |
View all methylphenidate prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Vyvanse | Aptensio XR, Concerta, Cotempla XR-ODT, Daytrana, Jornay PM, Metadate CD, Methylin, Methylin ER, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA View more | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
1 hour |
4 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 370 drugs are known to interact with lisdexamfetamine:
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A total of 198 drugs are known to interact with methylphenidate:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
February 23, 2007 |
December 05, 1955 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.