Comparing Lamotrigine vs Depakote ER
| Lamotrigine | Depakote ER |
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| Lamotrigine | Depakote ER (divalproex sodium) |
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Prescription only
Lamotrigine may be used to decrease the frequency and severity of seizures in some types of epilepsy and also to stabilize mood in bipolar disorder. Rarely, lamotrigine may cause a potentially fatal... View more |
Prescription only
Prescribed for Bipolar Disorder, Mania, Seizures, Migraine Prevention, Epilepsy. Depakote ER may also be used for purposes not listed in this medication guide. |
Related suggestions Migraine Prevention (Migraine Prophylaxis)
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| More about Lamotrigine | More about Depakote ER (divalproex sodium) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Lamotrigine has an average rating of 7.8 out of 10 from a total of 1806 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 15% reported a negative effect. |
Depakote ER has an average rating of 7.4 out of 10 from a total of 98 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 12% reported a negative effect. |
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| Side Effects | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Lamotrigine prices |
View all Depakote ER prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR, Subvenite | Other divalproex sodium brands include: Depakote, Depakote Sprinkles | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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25.7 hours |
16 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 286 drugs are known to interact with Lamotrigine:
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A total of 409 drugs are known to interact with Depakote ER:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 27, 1994 |
August 04, 2000 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.