Comparing Imipramine vs Nortriptyline
| Imipramine | Nortriptyline |
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| Imipramine | Nortriptyline |
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Prescription only
Prescribed for Enuresis, Interstitial Cystitis, Primary Nocturnal Enuresis, Pain, Depression, ADHD, Irritable Bowel Syndrome, Night Terrors, Panic Disorder, Somatoform Pain Disorder. Imipramine may... View more |
Prescription only
Nortriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. It may be used off-label to treat other conditions, such as... View more |
Related suggestions Depression
Panic Disorder
Irritable Bowel Syndrome
Popular comparisons
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| More about Imipramine | More about Nortriptyline | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Imipramine has an average rating of 7.3 out of 10 from a total of 79 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 19% reported a negative effect. |
Nortriptyline has an average rating of 7.3 out of 10 from a total of 567 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 19% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Imipramine side effects |
View all Nortriptyline side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Imipramine prices |
View all Nortriptyline prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Tofranil | Pamelor | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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20 hours |
31 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 736 drugs are known to interact with Imipramine:
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A total of 701 drugs are known to interact with Nortriptyline:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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April 16, 1959 |
November 06, 1964 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.