Comparing Hydroxyzine vs Promethazine
| Hydroxyzine | Promethazine |
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| Hydroxyzine | Promethazine |
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Prescription only
Hydroxyzine may be used to relieve anxiety or itching; however, it causes sedation so can affect a person's ability to drive or operate machinery. It should not be used during pregnancy or while... View more |
Prescription only
Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with several other drugs including antidepressants, antipsychotics, and other... View more |
Related suggestions Nausea/Vomiting
Allergies
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| More about Hydroxyzine | More about Promethazine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Hydroxyzine has an average rating of 5.9 out of 10 from a total of 1404 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 35% reported a negative effect. |
Promethazine has an average rating of 7.2 out of 10 from a total of 389 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Hydroxyzine side effects |
View all Promethazine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Hydroxyzine prices |
View all Promethazine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Vistaril | Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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7 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 581 drugs are known to interact with Hydroxyzine:
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A total of 688 drugs are known to interact with Promethazine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 12, 1956 |
March 29, 1951 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.