Harvoni Alternatives Compared
| Harvoni | Mavyret | Sofosbuvir |
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| Harvoni (ledipasvir / sofosbuvir) | Mavyret (glecaprevir / pibrentasvir) | Sofosbuvir |
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Prescription only
Harvoni is a combination tablet containing ledipasvir and sofosbuvir. It may be used to treat certain genotypes of the hepatitis C virus in adults and children over the age of three. It is usually... View more |
Prescription only
Mavyret is an antiviral combination agent that is approved to treat all six genotypes (1-6) of hepatitis C virus (HCV) in adults and children aged 12 years of age and older. It is one of the most... View more |
Prescription only
Prescribed for Hepatitis C. Sofosbuvir may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Harvoni (ledipasvir / sofosbuvir) | More about Mavyret (glecaprevir / pibrentasvir) | More about Sofosbuvir | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Harvoni has an average rating of 8.6 out of 10 from a total of 402 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 10% reported a negative effect. |
Mavyret has an average rating of 8.4 out of 10 from a total of 422 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 8% reported a negative effect. |
Sofosbuvir has an average rating of 7.6 out of 10 from a total of 51 ratings on Drugs.com. 72% of reviewers reported a positive effect, while 15% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all Harvoni prices |
View all Mavyret prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms Available | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
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N/A |
N/A |
Sovaldi | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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47 hours |
13 hours |
27 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category B
No proven risk in humans
Category X
Not for use in pregnancy
In Combination With Ribavirin Or Peginterferon Alfa/Ribavirin See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 175 drugs are known to interact with Harvoni:
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A total of 194 drugs are known to interact with Mavyret:
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A total of 82 drugs are known to interact with Sofosbuvir:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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October 10, 2014 |
August 03, 2017 |
December 06, 2013 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.