Comparing Fosamax vs Zometa
| Fosamax (alendronate) | Zometa (zoledronic acid) |
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| Fosamax (alendronate) | Zometa (zoledronic acid) |
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Prescription only
Fosamax helps to reduce the risk of fracture in people with osteoporosis and some other bone conditions. Dosage instructions, including remaining upright for at least 30 minutes and taking with a... View more |
Prescription only
Zometa is only available as an injection for administration by a healthcare provider and is indicated for the treatment of hypercalcemia associated with cancer, osteolytic bone lesions of multiple... View more |
Related suggestions Osteoporosis
Paget's Disease
Popular comparisons
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| More about Fosamax (alendronate) | More about Zometa (zoledronic acid) | ||||||||
| Ratings & Reviews | |||||||||
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Fosamax has an average rating of 2.8 out of 10 from a total of 76 ratings on Drugs.com. 18% of reviewers reported a positive effect, while 80% reported a negative effect. |
Zometa has an average rating of 4.8 out of 10 from a total of 43 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 51% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Fosamax side effects |
View all Zometa side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Lower cost generic approved | |||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Fosamax prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Other alendronate brands include: Binosto | Other zoledronic acid brands include: Aclasta, Reclast | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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N/A |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 117 drugs are known to interact with Fosamax:
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A total of 123 drugs are known to interact with Zometa:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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September 29, 1995 |
February 22, 2002 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.