Comparing Fioricet vs Fiorinal

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Fioricet (acetaminophen / butalbital / caffeine)	Fiorinal (aspirin / butalbital / caffeine)	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Fioricet (acetaminophen / butalbital / caffeine)	Fiorinal (aspirin / butalbital / caffeine)	Enter another drug to compare
Prescription only Fioricet may be used for the short-term treatment of tension-type headaches; however, it is not a first-choice medicine because it is potentially habit-forming and causes sedation. Simpler and safer... View more	Prescription only Prescribed for Headache, Migraine, Pain. Fiorinal may also be used for purposes not listed in this medication guide.	Related suggestions Headache Ibuprofen Acetaminophen / butalbital / caffeine OnabotulinumtoxinA Erenumab Ubrogepant Eptinezumab Popular comparisons Fioricet vs ibuprofen
More about Fioricet (acetaminophen / butalbital / caffeine)	More about Fiorinal (aspirin / butalbital / caffeine)
Ratings & Reviews
Fioricet has an average rating of 8.7 out of 10 from a total of 169 ratings on Drugs.com. 85% of reviewers reported a positive effect, while 8% reported a negative effect.	Fiorinal has an average rating of 8.9 out of 10 from a total of 76 ratings on Drugs.com. 87% of reviewers reported a positive effect, while 8% reported a negative effect.
View all 169 reviews	View all 76 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Headaches (7.7%) Anxiety (3.6%) Drowsiness (3.0%) Nausea (3.0%) Dizziness (2.4%) Migraine (1.8%) Sleepy (1.8%) View all Fioricet side effects	Drowsiness (7.9%) Nausea (3.9%) Vomiting (3.9%) View all Fiorinal side effects
Drug Class
Analgesic combinations	Analgesic combinations
Generic Availability
N/A	Lower cost generic approved
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
Oral capsule Oral tablet	Oral capsule
Brand Names
Other acetaminophen / butalbital / caffeine brands include: Anolor 300, Capacet, Phrenilin Forte, Vanatol LQ, Vanatol S, Vtol LQ, Zebutal	Other aspirin / butalbital / caffeine brands include: Farbital, Fiormor, Fiortal, Fortabs
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
35 hours	35 hours
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	3 Moderate abuse potential Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
Pregnancy Category
C Category C Risk cannot be ruled out See the full pregnancy warnings document.	C Category C Risk cannot be ruled out See the full pregnancy warnings document.
Drug Interactions
A total of 713 drugs are known to interact with Fioricet: 47 major drug interactions (197 brand and generic names) 613 moderate drug interactions (2815 brand and generic names) 53 minor drug interactions (265 brand and generic names)	A total of 887 drugs are known to interact with Fiorinal: 98 major drug interactions (378 brand and generic names) 734 moderate drug interactions (3525 brand and generic names) 55 minor drug interactions (224 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Ask your doctor before using acetaminophen together with alcohol. This can cause serious side... View more	Ask your doctor before using butalbital together with alcohol, this can add to dizziness... View more
Disease Interactions
Alcoholism Liver disease Acute alcohol intoxication Drug dependence Liver disease Porphyria Rash Respiratory depression Cardiac disease Hypertension Psychiatric disorders PUD PKU Adrenal insufficiency Depression Hematologic toxicity Osteomalacia Paradoxical reactions Cardiotoxicity Liver disease Renal dysfunction Seizure disorders GERD	Coagulation Acute alcohol intoxication Drug dependence Liver disease Porphyria Rash Respiratory depression Cardiac disease Hypertension Psychiatric disorders PUD Asthma GI toxicity Renal dysfunction Reye's syndrome Adrenal insufficiency Depression Hematologic toxicity Osteomalacia Paradoxical reactions Cardiotoxicity Liver disease Renal dysfunction Seizure disorders GERD Anemia Dialysis G-6-PD deficiency Hepatotoxicity
First Approval Date
N/A	May 04, 1976
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pricing and coupons Pregnancy warnings Drug images Support group En español	Side effects Drug interactions Dosage Pregnancy warnings Drug images Support group
Patient Resources
Fioricet uses	Fiorinal uses
Professional Resources
Prescribing information	Prescribing information
Related Treatment Guide
Headache	Headache Migraine Pain

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

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Comparing Fioricet vs Fiorinal

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