Comparing Etanercept vs Tocilizumab

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Etanercept	Tocilizumab	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Etanercept	Tocilizumab	Enter another drug to compare
Prescription only Prescribed for Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Plaque Psoriasis, Juvenile Rheumatoid Arthritis, Polyarticular Juvenile Idiopathic Arthritis, Alzheimer's Disease... View more	Prescription only Prescribed for Giant Cell Arteritis, Cytokine Release Syndrome, COVID-19, Rheumatoid Arthritis, Juvenile Idiopathic Arthritis, Polyarticular Juvenile Idiopathic Arthritis, Still's Disease, Systemic... View more	Related suggestions Rheumatoid Arthritis Methotrexate Hydroxychloroquine Prednisone Meloxicam Celebrex Plaquenil Still's Disease Anakinra Canakinumab Ilaris Polyarticular Juvenile Idiopathic Arthritis Naproxen Xeljanz Methotrexate Rasuvo Upadacitinib Rinvoq Popular comparisons Etanercept vs anakinra
More about Etanercept	More about Tocilizumab
Ratings & Reviews
Etanercept has an average rating of 7.8 out of 10 from a total of 321 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 13% reported a negative effect.	Tocilizumab has an average rating of 6.8 out of 10 from a total of 54 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 20% reported a negative effect.
View all 321 reviews	View all 54 reviews
Drug Class
Antirheumatics TNF alfa inhibitors	Interleukin inhibitors
Side Effects
See also: etanercept side effects in more detail.	See also: tocilizumab side effects in more detail.
Generic Availability
N/A	N/A
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms Available
N/A	N/A
Brand Names
Enbrel, Erelzi, Eticovo	Actemra, Tofidence, Tyenne
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.
300 hours	210 hours
CSA Schedule ** View glossary of terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
B Category B No proven risk in humans See the full pregnancy warnings document.	C Category C Risk cannot be ruled out See the full pregnancy warnings document.
Drug Interactions
A total of 425 drugs are known to interact with etanercept: 292 major drug interactions (850 brand and generic names) 125 moderate drug interactions (360 brand and generic names) 8 minor drug interactions (35 brand and generic names)	A total of 402 drugs are known to interact with tocilizumab: 58 major drug interactions (161 brand and generic names) 337 moderate drug interactions (1165 brand and generic names) 7 minor drug interactions (34 brand and generic names)
Alcohol/Food/Lifestyle Interactions
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.	No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease Interactions
Hepatitis B Infections Tuberculosis Alcoholic hepatitis Heart failure Hematologic abnormalities Hypoglycemia Nervous system disorders Varicella Wegener's granulomatosis	Infections Tuberculosis Demyelinating disorders Gastrointestinal perforation Lipid abnormalities Liver dysfunction Neutropenia/thrombocytopenia Renal impairment
First Approval Date
November 02, 1998	N/A
WADA Class View World Anti-Doping Agency classifications.
N/A	N/A
More Information
Side effects Pregnancy warnings Breastfeeding warnings Dosage information Drug interactions Support group	Side effects Pregnancy warnings Breastfeeding warnings Dosage information Drug interactions Support group En Español
Patient resources
Etanercept uses Advanced reading	Tocilizumab uses Advanced reading
Professional Resources
Monograph (AHFS) Prescribing information	Monograph (AHFS) Prescribing information
Related Treatment Guide
Rheumatoid Arthritis Ankylosing Spondylitis Psoriatic Arthritis Plaque Psoriasis Juvenile Rheumatoid Arthritis Polyarticular Juvenile Idiopathic Arthritis Alzheimer's Disease Behcet's Disease Bullous Pemphigoid Cogan's Syndrome Granulomatosis with Polyangiitis Histiocytosis Macrophage Activation Syndrome Pemphigoid Pemphigus Psoriasis SAPHO Syndrome Spondyloarthritis Still's Disease Uveitis show all	Giant Cell Arteritis Cytokine Release Syndrome COVID-19 Rheumatoid Arthritis Juvenile Idiopathic Arthritis Polyarticular Juvenile Idiopathic Arthritis Still's Disease Systemic Sclerosis Systemic Sclerosis-Associated Interstitial Lung Disease show all

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

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Comparing Etanercept vs Tocilizumab

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