Epclusa Alternatives Compared
| Epclusa (sofosbuvir / velpatasvir) | Harvoni (ledipasvir / sofosbuvir) | Ribavirin |
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| Epclusa (sofosbuvir / velpatasvir) | Harvoni (ledipasvir / sofosbuvir) | Ribavirin |
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Prescription only
Epclusa is a combination tablet containing velpatasvir and sofosbuvir. It may be used to treat all six genotypes of the hepatitis C virus in adults and children over the age of three. It is usually... View more |
Prescription only
Harvoni is a combination tablet containing ledipasvir and sofosbuvir. It may be used to treat certain genotypes of the hepatitis C virus in adults and children over the age of three. It is usually... View more |
Prescription only
Prescribed for RSV, Hepatitis C. Ribavirin may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Epclusa (sofosbuvir / velpatasvir) | More about Harvoni (ledipasvir / sofosbuvir) | More about Ribavirin | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Epclusa has an average rating of 7.6 out of 10 from a total of 398 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 12% reported a negative effect. |
Harvoni has an average rating of 8.4 out of 10 from a total of 403 ratings on Drugs.com. 78% of reviewers reported a positive effect, while 11% reported a negative effect. |
Ribavirin has an average rating of 4.8 out of 10 from a total of 10 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 50% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Epclusa side effects |
View all Harvoni side effects |
View all Ribavirin side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Epclusa prices |
View all Harvoni prices |
View all Ribavirin prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
Rebetol, RibaTab, Virazole | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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27 hours |
47 hours |
960 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 195 drugs are known to interact with Epclusa:
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A total of 177 drugs are known to interact with Harvoni:
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A total of 18 drugs are known to interact with Ribavirin:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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June 28, 2016 |
October 10, 2014 |
June 03, 1998 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.