Comparing Entresto vs Losartan
| Entresto (sacubitril / valsartan) | Losartan |
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| Entresto (sacubitril / valsartan) | Losartan |
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Prescription only
Entresto is a combination medication containing sacubitril and valsartan that may be given to treat heart failure in adults and children over the age of one. Studies have shown it to be superior to... View more |
Prescription only
Losartan works on a hormone called angiotensin II to lower blood pressure and may also improve kidney function in some people. People being initiated on losartan should be adequately rehydrated and... View more |
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| More about Entresto (sacubitril / valsartan) | More about Losartan | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Entresto has an average rating of 5.0 out of 10 from a total of 200 ratings on Drugs.com. 39% of reviewers reported a positive effect, while 48% reported a negative effect. |
Losartan has an average rating of 4.5 out of 10 from a total of 578 ratings on Drugs.com. 26% of reviewers reported a positive effect, while 48% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Entresto side effects |
View all Losartan side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Entresto prices |
View all Losartan prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other sacubitril / valsartan brands include: Entresto Sprinkle | Arbli, Cozaar | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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11.5 hours |
4.4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 348 drugs are known to interact with Entresto:
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A total of 324 drugs are known to interact with Losartan:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 07, 2015 |
April 14, 1995 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.