Comparing Duloxetine vs Savella
| Duloxetine | Savella (milnacipran) |
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| Duloxetine | Savella (milnacipran) |
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Prescription only
Duloxetine has antidepressant, anti-anxiety, and pain-relieving properties; however, it may cause a discontinuation syndrome on withdrawal even when tapered. Symptoms may include anxiety, headache... View more |
Prescription only
Prescribed for Fibromyalgia. Savella may also be used for purposes not listed in this medication guide. |
Related suggestions Fibromyalgia
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| More about Duloxetine | More about Savella (milnacipran) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Duloxetine has an average rating of 6.2 out of 10 from a total of 2458 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 31% reported a negative effect. |
Savella has an average rating of 6.7 out of 10 from a total of 347 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Duloxetine side effects |
View all Savella side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Duloxetine prices |
View all Savella prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Cymbalta, Drizalma Sprinkle, Irenka |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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17 hours |
10 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 628 drugs are known to interact with Duloxetine:
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A total of 383 drugs are known to interact with Savella:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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August 03, 2004 |
January 14, 2009 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.