Comparing Duloxetine vs Imipramine
| Duloxetine | Imipramine |
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| Duloxetine | Imipramine |
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Prescription only
Duloxetine has antidepressant, anti-anxiety, and pain-relieving properties; however, it may cause a discontinuation syndrome on withdrawal even when tapered. Symptoms may include anxiety, headache... View more |
Prescription only
Prescribed for Enuresis, Interstitial Cystitis, Primary Nocturnal Enuresis, Pain, Depression, ADHD, Irritable Bowel Syndrome, Night Terrors, Panic Disorder, Somatoform Pain Disorder. Imipramine may... View more |
Related suggestions Depression
Somatoform Pain Disorder
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| More about Duloxetine | More about Imipramine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Duloxetine has an average rating of 6.2 out of 10 from a total of 2458 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 31% reported a negative effect. |
Imipramine has an average rating of 7.3 out of 10 from a total of 79 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 19% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Duloxetine side effects |
View all Imipramine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Duloxetine prices |
View all Imipramine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Cymbalta, Drizalma Sprinkle, Irenka | Tofranil | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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17 hours |
20 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 628 drugs are known to interact with Duloxetine:
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A total of 738 drugs are known to interact with Imipramine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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August 03, 2004 |
April 16, 1959 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.