Comparing Divalproex Sodium vs Topiramate
Divalproex sodium | Topiramate |
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Divalproex sodium | Topiramate |
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Prescription only
Divalproex may be used for the treatment of absence or partial seizures, as a preventive treatment for migraines, and to treat mania associated with bipolar disorder. Divalproex may adversely and... View more |
Prescription only
Topiramate may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraines. Drowsiness is a... View more |
Related suggestions Migraine Prevention (Migraine Prophylaxis)
Popular comparisons
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More about Divalproex sodium | More about Topiramate | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Divalproex sodium has an average rating of 6.6 out of 10 from a total of 502 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 24% reported a negative effect. |
Topiramate has an average rating of 6.3 out of 10 from a total of 1322 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 28% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: divalproex sodium side effects in more detail. |
See also: topiramate side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all divalproex sodium prices |
View all topiramate prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Depakote, Depakote ER, Depakote Sprinkles | Eprontia, Qudexy XR, Topamax, Trokendi XR | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
16 hours |
56 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 409 drugs are known to interact with divalproex sodium:
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A total of 289 drugs are known to interact with topiramate:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
March 10, 1983 |
December 24, 1996 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.