Comparing Dextromethorphan vs Guaifenesin
| Dextromethorphan | Guaifenesin |
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| Dextromethorphan | Guaifenesin |
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Prescription and OTC
Prescribed for Cough. Dextromethorphan may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Guaifenesin is an expectorant that helps thin and remove mucus from the airways. It is generally well tolerated. Prescribed for Bronchitis, Bronchiectasis, Cough, Fibromyalgia. Guaifenesin may also... View more |
Related suggestions |
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| More about Dextromethorphan | More about Guaifenesin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Dextromethorphan has an average rating of 3.7 out of 10 from a total of 386 ratings on Drugs.com. 20% of reviewers reported a positive effect, while 63% reported a negative effect. |
Guaifenesin has an average rating of 7.1 out of 10 from a total of 305 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 24% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Dextromethorphan side effects |
View all Guaifenesin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Dextromethorphan prices |
View all Guaifenesin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| 12 Hour Cough Relief, Babee Cof, Balminil DM, Benadryl for the Family Dry Forte, Benylin DM, Bisolvon Dry, Bisolvon Dry Junior, Buckley's DM, Buckley's Mixture Cough Suppressant, Buckleys Mixture, Calmylin, Contac Cough, Cough Syrup DM, Covonia Bronchial Balsam, Creomulsion, Creomulsion Children, Delsym, Delsym 12 Hour Cough Relief, Delsym 12 Hour Cough Relief for Children & Adults, Delsym Children's 12-Hour Cough Relief, DexAlone, Dexi-Tuss, Dextromethorphan HBr Adult Formula, Dristan DM, Dry Cough, Duract Max Strength Cough, ElixSure Cough, Giltuss Children's Honey DM 8hr Cough, Giltuss Honey DM 8hr Cough, Hold, Hold DM, Robafen Cough Liquidgels, Robitussin 12-Hour Cough Relief, Robitussin Children's Cough Long-Acting, Robitussin Cough Long-Acting, Robitussin CoughGels Long-Acting, Robitussin Direct Cough, Scot-Tussin Diabetes, Silphen DM, Sucrets Cough, Triaminic Long Acting Cough, Triaminic Thin Strips Cough, Tussin Cough Gels (Long Acting), Vicks Dayquil Cough, Vicks Formula 44, Vicks Formula 44 Custom Care Dry Cough Suppressant, Vicks Nature Fusion Cough View more | Air Power, Allfen Jr, Altarussin, Altorant, Amibid LA, Anti-Tuss, Aquamist, Balminil Expectorant, Beechams Veno's Expectorant, Beechams Veno's for Kids Chesty Cough, Benadryl Chesty Forte, Benylin E, Bidex-400, Breonesin, Bronchoril, Buckley's Chest Congestion, Calmylin Expectorant, Diabetic Expectorant, Diabetic Tuss, Diabetic Tussin Chest Congestion, Diabetic Tussin Mucus Relief, Dristan Chesty Cough, Dristan Chesty Cough Guaiphenesin, Drituss G, Duratuss G, Family Meltus Chesty Coughs, Fenesin, Fenesin IR, Fenex-LA, G Bid, Ganidin NR, Genatuss, GG 200 NR, GG-Cen, Giltuss Children's EX Expectorant, Giltuss EX Expectorant, Glytuss, Gua-SR, Guaiatussin, Guaibid-LA, Guaifen NR, Guaifenesin LA, Guaifenex G, Guaifenex LA, Guiacough, Guiadrine G-1200, Guiatuss, Help I Have Chest Congestion, Hill's Balsam Chesty Cough, Humavent LA, Humibid, Humibid E, Humibid Pediatric, Humigen LA, Hytuss, Junior Meltus Chesty Coughs with Catarrh, Junior Meltus Colour and Sugar Free Expectorant, Lemsip Cough Chesty, Mucaplex, Mucinex, Mucinex Children's Chest Congestion, Mucinex for Kids, Mucinex Maximum Strength, Mucobid-LA, Organ-1 NR, Refenesen Chest Congestion Relief, Robafen, Robitussin Mucus + Chest Congestion, Rompe Pecho EX, Scot-Tussin Expectorant, Siltuss DAS, Siltussin DAS, Siltussin DAS-NA, TabTussin 400, Tussin Expectorant, Tussin Mucus + Chest Congestion, Xpect View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.6 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 367 drugs are known to interact with Dextromethorphan:
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No known drug interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||||||||||
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October 08, 1982 |
July 12, 2002 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.