Desyrel Alternatives Compared
| Desyrel (trazodone) | Trintellix (vortioxetine) | Vraylar (cariprazine) |
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| Desyrel (trazodone) | Trintellix (vortioxetine) | Vraylar (cariprazine) |
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Prescription only
Prescribed for Fibromyalgia, Depression, Major Depressive Disorder, Sedation, Reflex Sympathetic Dystrophy Syndrome. Desyrel may also be used for purposes not listed in this medication guide. |
Prescription only
Trintellix may be used to treat depression in adults. It is different from other antidepressants currently on the market because it directly affects serotonin receptors as well as inhibits serotonin... View more |
Prescription only
Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... View more |
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| More about Desyrel (trazodone) | More about Trintellix (vortioxetine) | More about Vraylar (cariprazine) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Desyrel has an average rating of 6.5 out of 10 from a total of 39 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 21% reported a negative effect. |
Trintellix has an average rating of 6.0 out of 10 from a total of 1119 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 33% reported a negative effect. |
Vraylar has an average rating of 6.0 out of 10 from a total of 505 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Trintellix prices |
View all Vraylar prices |
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| Dosage Forms Available | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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7.5 hours |
66 hours |
504 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 653 drugs are known to interact with Desyrel:
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A total of 352 drugs are known to interact with Trintellix:
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A total of 571 drugs are known to interact with Vraylar:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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December 24, 1981 |
September 30, 2013 |
September 17, 2015 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.