Comparing Depakote vs Keppra
| Depakote (divalproex sodium) | Keppra (levetiracetam) |
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| Depakote (divalproex sodium) | Keppra (levetiracetam) |
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Prescription only
Depakote may be used in the treatment of epilepsy and mania, and to prevent migraines; however, people taking Depakote should be monitored for potentially fatal side effects such as liver failure... View more |
Prescription only
Keppra is an anticonvulsant that is used in conjunction with other medications for the treatment of certain types of seizures. It may cause drowsiness but it is less likely than some other... View more |
Related suggestions |
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| More about Depakote (divalproex sodium) | More about Keppra (levetiracetam) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Depakote has an average rating of 6.3 out of 10 from a total of 329 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 26% reported a negative effect. |
Keppra has an average rating of 5.7 out of 10 from a total of 307 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Depakote side effects |
View all Keppra side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Depakote prices |
View all Keppra prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other divalproex sodium brands include: Depakote ER, Depakote Sprinkles | Other levetiracetam brands include: Elepsia XR, Keppra XR, Roweepra, Roweepra XR, Spritam | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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16 hours |
8 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 424 drugs are known to interact with Depakote:
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A total of 238 drugs are known to interact with Keppra:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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March 10, 1983 |
November 30, 1999 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.