Comparing Depakote ER vs Phenytoin
Depakote ER | Phenytoin |
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Depakote ER (divalproex sodium) | Phenytoin |
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Prescription only
Prescribed for Bipolar Disorder, Mania, Migraine Prevention, Seizures, Epilepsy. Depakote ER may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Epilepsy, Seizures, Anxiety, Neurosurgery, Cluster-Tic Syndrome, Seizure Prophylaxis During or Following Neurosurgery, Status Epilepticus, Arrhythmia, Myotonia Congenita, Peripheral... View more |
Related suggestions |
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More about Depakote ER (divalproex sodium) | More about Phenytoin | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Depakote ER has an average rating of 7.4 out of 10 from a total of 98 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 12% reported a negative effect. |
Phenytoin has an average rating of 7.6 out of 10 from a total of 113 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 17% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Depakote ER side effects in more detail. |
See also: phenytoin side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Depakote ER prices |
View all phenytoin prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other divalproex sodium brands include: Depakote, Depakote Sprinkles | Di-Phen, Dilantin, Phenytek, Phenytoin Sodium, Phenytoin Sodium, Extended Release | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
16 hours |
15 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 409 drugs are known to interact with Depakote ER:
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A total of 839 drugs are known to interact with phenytoin:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
August 04, 2000 |
January 06, 1953 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.