Comparing Contrave vs Metformin
| Contrave | Metformin |
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| Contrave (bupropion / naltrexone) | Metformin |
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Prescription only
Prescribed for Weight Loss (Obesity/Overweight). Contrave may also be used for purposes not listed in this medication guide. |
Prescription only
Metformin improves how the body responds to insulin and it is effective for the treatment of type 2 diabetes. Taste disturbances, diarrhea, and other stomach-related side effects are common side... View more |
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| More about Contrave (bupropion / naltrexone) | More about Metformin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Contrave has an average rating of 6.6 out of 10 from a total of 1982 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 25% reported a negative effect. |
Metformin has an average rating of 6.9 out of 10 from a total of 652 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 19% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Contrave prices |
View all Metformin prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Glumetza | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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21 hours |
4.5 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 749 drugs are known to interact with Contrave:
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A total of 370 drugs are known to interact with Metformin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 10, 2014 |
March 03, 1995 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.