Comparing Codeine vs Tapentadol
| Codeine | Tapentadol |
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| Codeine | Tapentadol |
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Prescription only
Codeine is used to relieve mild-to-moderate pain where treatment with an opioid is appropriate. However, it is addictive, may cause constipation and drowsiness, and its pain-relieving effects vary... View more |
Prescription only
Prescribed for Pain, Diabetic Peripheral Neuropathy. Tapentadol may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Codeine | More about Tapentadol | ||||||||
| Ratings & Reviews | |||||||||
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Codeine has an average rating of 7.8 out of 10 from a total of 70 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 16% reported a negative effect. |
Tapentadol has an average rating of 6.4 out of 10 from a total of 436 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 27% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Codeine side effects |
View all Tapentadol side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Codeine prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
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N/A |
Nucynta, Nucynta ER | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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3.5 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 524 drugs are known to interact with Codeine:
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A total of 398 drugs are known to interact with Tapentadol:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
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| First Approval Date | |||||||||
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July 16, 2009 |
November 20, 2008 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.