Comparing Codeine vs Dextromethorphan
| Codeine | Dextromethorphan |
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| Codeine | Dextromethorphan |
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Prescription only
Codeine is used to relieve mild-to-moderate pain where treatment with an opioid is appropriate. However, it is addictive, may cause constipation and drowsiness, and its pain-relieving effects vary... View more |
Prescription and OTC
Prescribed for Cough. Dextromethorphan may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Codeine | More about Dextromethorphan | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Codeine has an average rating of 7.8 out of 10 from a total of 70 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 16% reported a negative effect. |
Dextromethorphan has an average rating of 3.7 out of 10 from a total of 386 ratings on Drugs.com. 20% of reviewers reported a positive effect, while 63% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Codeine side effects |
View all Dextromethorphan side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Codeine prices |
View all Dextromethorphan prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
12 Hour Cough Relief, Babee Cof, Balminil DM, Benadryl for the Family Dry Forte, Benylin DM, Bisolvon Dry, Bisolvon Dry Junior, Buckley's DM, Buckley's Mixture Cough Suppressant, Buckleys Mixture, Calmylin, Contac Cough, Cough Syrup DM, Covonia Bronchial Balsam, Creomulsion, Creomulsion Children, Delsym, Delsym 12 Hour Cough Relief, Delsym 12 Hour Cough Relief for Children & Adults, Delsym Children's 12-Hour Cough Relief, DexAlone, Dexi-Tuss, Dextromethorphan HBr Adult Formula, Dristan DM, Dry Cough, Duract Max Strength Cough, ElixSure Cough, Giltuss Children's Honey DM 8hr Cough, Giltuss Honey DM 8hr Cough, Hold, Hold DM, Robafen Cough Liquidgels, Robitussin 12-Hour Cough Relief, Robitussin Children's Cough Long-Acting, Robitussin Cough Long-Acting, Robitussin CoughGels Long-Acting, Robitussin Direct Cough, Scot-Tussin Diabetes, Silphen DM, Sucrets Cough, Triaminic Long Acting Cough, Triaminic Thin Strips Cough, Tussin Cough Gels (Long Acting), Vicks Dayquil Cough, Vicks Formula 44, Vicks Formula 44 Custom Care Dry Cough Suppressant, Vicks Nature Fusion Cough View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.5 hours |
3.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 524 drugs are known to interact with Codeine:
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A total of 367 drugs are known to interact with Dextromethorphan:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||||||||||
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July 16, 2009 |
October 08, 1982 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.