Comparing Codeine / Guaifenesin vs Promethazine
| Codeine / guaifenesin | Promethazine |
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| Codeine / guaifenesin | Promethazine |
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Prescription only
Prescribed for Cough. Codeine / guaifenesin may also be used for purposes not listed in this medication guide. |
Prescription only
Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with several other drugs including antidepressants, antipsychotics, and other... View more |
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| More about Codeine / guaifenesin | More about Promethazine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Codeine / guaifenesin has an average rating of 5.6 out of 10 from a total of 87 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 41% reported a negative effect. |
Promethazine has an average rating of 7.2 out of 10 from a total of 389 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Codeine / guaifenesin side effects |
View all Promethazine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Codeine / guaifenesin prices |
View all Promethazine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Allfen CD, Allfen CDX, Bitex Liquid, Brontex, Cheracol with Codeine, Cheratussin AC, Codafen, Codar GF, Dex-Tuss, Diabetic Tussin C, Duraganidin NR, ExeClear-C, Gani-Tuss NR, Glydeine, Guai-Co, Guaiatussin AC, Guaifen AC, Guaifen-C, Guaifenesin AC, Guaitussin AC, Guiatuss AC, Guiatussin with Codeine, M-Clear WC, Mar-cof CG, Mytussin AC, Pro-Clear, Robafen AC, Virtussin A/C View more | Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.5 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Multiple
The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 524 drugs are known to interact with Codeine / guaifenesin:
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A total of 688 drugs are known to interact with Promethazine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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N/A |
March 29, 1951 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.