Codeine Alternatives Compared
| Codeine | Tramadol | Gabapentin |
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| Codeine | Tramadol | Gabapentin |
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Prescription only
Codeine is used to relieve mild-to-moderate pain where treatment with an opioid is appropriate. However, it is addictive, may cause constipation and drowsiness, and its pain-relieving effects vary... View more |
Prescription only
Tramadol is a strong opioid pain relieving medication that may be used to treat moderate to severe general and nerve-related pain. Tramadol may be habit-forming and misuse can cause addiction... View more |
Prescription only
Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may... View more |
Related suggestions |
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| More about Codeine | More about Tramadol | More about Gabapentin | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Codeine has an average rating of 7.8 out of 10 from a total of 71 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 15% reported a negative effect. |
Tramadol has an average rating of 7.0 out of 10 from a total of 1884 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 23% reported a negative effect. |
Gabapentin has an average rating of 7.1 out of 10 from a total of 2583 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Codeine side effects |
View all Tramadol side effects |
View all Gabapentin side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Codeine prices |
View all Tramadol prices |
View all Gabapentin prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
ConZip, Qdolo, Tramadol Hydrochloride ER | Fanatrex, Gabarone, Gralise, Neurontin | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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3.5 hours |
5.2 hours |
6 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 525 drugs are known to interact with Codeine:
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A total of 713 drugs are known to interact with Tramadol:
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A total of 271 drugs are known to interact with Gabapentin:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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July 16, 2009 |
March 03, 1995 |
December 30, 1993 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.