Comparing Clomipramine vs Naltrexone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Clomipramine	Naltrexone	Enter another drug to compare

Clomipramine

Naltrexone

Prescription only

Prescribed for Obsessive Compulsive Disorder, Irritable Bowel Syndrome, Depression, Panic Disorder, Premature Ejaculation, Sleep Paralysis, Trichotillomania. Clomipramine may also be used for... View more

Prescription only

Naltrexone is used as an adjunct to social and psychotherapy in the treatment of opioid and alcohol addiction. People taking naltrexone need to have completely stopped taking all types of opioids... View more

More about Clomipramine

More about Naltrexone

Ratings & Reviews

Clomipramine has an average rating of 8.0 out of 10 from a total of 312 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 13% reported a negative effect.

Naltrexone has an average rating of 7.9 out of 10 from a total of 600 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 16% reported a negative effect.

View all 312 reviews

View all 600 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Dry mouth (15.1%)
Sexual dysfunction (10.9%)
Constipation (10.6%)
Anxiety (7.7%)
Weight gain (7.1%)
Insomnia (6.4%)
Tiredness (5.1%)

View all Clomipramine side effects

Nausea (8.2%)
Anxiety (7.2%)
Tiredness (6.5%)
Depression (6.0%)
Insomnia (5.7%)
Fatigue (5.0%)
Headaches (4.7%)

View all Naltrexone side effects

Drug Class

Tricyclic antidepressants

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	30 each
Strength	25 mg
Per unit^*	$8.16 - $10.77
Cost^*	$244.85 - $323.24

View all Clomipramine prices

Quantity	20 each
Strength	50 mg
Per unit^*	$1.75
Cost^*	$34.97

View all Naltrexone prices

Get free Discount Card

Dosage Forms

Oral capsule

Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

18 hours

10 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 792 drugs are known to interact with Clomipramine:

143 major drug interactions (602 brand and generic names)
624 moderate drug interactions (2556 brand and generic names)
25 minor drug interactions (159 brand and generic names)

A total of 349 drugs are known to interact with Naltrexone:

34 major drug interactions (160 brand and generic names)
315 moderate drug interactions (1313 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Grapefruit, grapefruit juice, and cranberry juice may cause the clomiPRAMINE levels in your body to... View more
Ask your doctor before using clomiPRAMINE together with alcohol, this can alter the effects of... View more

Naltrexone may cause liver problems, and using it with other medications that can also affect the... View more

Disease Interactions

First Approval Date

December 29, 1989

November 20, 1984

WADA Class View classifications

N/A

More Information

Patient Resources

Naltrexone uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Clomipramine vs Naltrexone

Further information

Compare Drugs