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Comparing Chloroquine vs Malarone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Chloroquine Malarone (atovaquone / proguanil)
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Chloroquine Malarone (atovaquone / proguanil)
Prescription only

Prescribed for Malaria, Malaria Prevention, Sarcoidosis, Amebiasis. Chloroquine may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Malaria Prevention, Malaria. Malarone may also be used for purposes not listed in this medication guide.

More about Chloroquine More about Malarone (atovaquone / proguanil)
Ratings & Reviews

Chloroquine has an average rating of 10.0 out of 10 from a total of 2 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect.

Malarone has an average rating of 5.5 out of 10 from a total of 45 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 40% reported a negative effect.

View all 2 reviews

View all 45 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Chloroquine side effects

View all Malarone side effects
Drug Class
Generic Availability

Lower cost generic

Lower cost generic approved
Pricing and Coupons * Prices are without insurance
Quantity 25 tablet
Strength 500 mg
Per unit* $7.56
Cost* $188.90

View all Chloroquine prices

Quantity 24 tablet
Strength 250 mg-100 mg
Per unit* $7.75
Cost* $185.93

View all Malarone prices

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Dosage Forms
  • Oral tablet
  • Oral tablet
Brand Names

N/A

 Other atovaquone / proguanil brands include: Malarone Pediatric
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

282 hours

60.5 hours
CSA Schedule 1 View glossary of CSA terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
N
Category N Not classified

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
Drug Interactions

A total of 527 drugs are known to interact with Chloroquine:

  • 199 major drug interactions (623 brand and generic names)
  • 314 moderate drug interactions (1262 brand and generic names)
  • 14 minor drug interactions (48 brand and generic names)

A total of 122 drugs are known to interact with Malarone:

  • 13 major drug interactions (27 brand and generic names)
  • 102 moderate drug interactions (578 brand and generic names)
  • 7 minor drug interactions (21 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • You may want to limit your consumption of grapefruit or grapefruit juice during treatment with... View more
  • Food significantly enhances the absorption of atovaquone. You should take each dose of atovaquone... View more
Disease Interactions
First Approval Date

October 31, 1949

July 14, 2000
WADA Class View classifications

N/A

N/A
More Information
Patient Resources
Professional Resources
Related Treatment Guide

1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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