Comparing Caffeine vs Methylphenidate
| Caffeine | Methylphenidate |
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| Caffeine | Methylphenidate |
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Prescription and OTC
Prescribed for Drowsiness, Apnea of Prematurity, Asthma. Caffeine may also be used for purposes not listed in this medication guide. |
Prescription only
Methylphenidate can help improve symptoms of ADHD but may cause dependence and side effects include a headache, loss of appetite, and sleeplessness. It is recommended that methylphenidate should not... View more |
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| More about Caffeine | More about Methylphenidate | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Caffeine has an average rating of 6.7 out of 10 from a total of 39 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 28% reported a negative effect. |
Methylphenidate has an average rating of 7.2 out of 10 from a total of 1082 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Caffeine side effects |
View all Methylphenidate side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Caffeine prices |
View all Methylphenidate prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| 357 HR Magnum, Alert, Cafcit, Caffedrine, ConRx Alert, Diurex Maximum Relief Water Caps, Diurex Ultra, Enerjets, Fastlene, Jet Alert Double Strength, Jet Alert Maximum Strength, Jet Alert Regular Strength, Keep Going, Molie, NoDoz, Overtime, Pep-Back ReCharge, Pep-Back Ultra, Stay Awake, Valentine, Vivarin View more | Aptensio XR, Concerta, Cotempla XR-ODT, Daytrana, Jornay PM, Metadate CD, Methylin, Methylin ER, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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4 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
Caffeine Citrate Injection
Category N
Not classified
Excluding Caffeine Citrate Injection See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 107 drugs are known to interact with Caffeine:
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A total of 207 drugs are known to interact with Methylphenidate:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 21, 1999 |
December 05, 1955 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.